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AZD-9291 mesylate

CAT: 0026-B1899-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1899-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD9291 is a potent, selective, and irreversible, third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It inhibits EGFR phosphorylation in EGFR-bearing cells harboring sensitizing EGFR mutants with mean IC₅₀ values ranging from 13 to 54 nM. It also potently inhibits phosphorylation of EGFR in T790M+ mutant cell lines. AZD-9291 displays profound and sustained tumor regression in EGFR-mutant tumor xenograft and transgenic models.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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