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Tropodithietic Acid

CAT: 0026-B1867-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-B1867-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tropodithietic acid is a broad spectrum tropolone antibiotic with activity against both Gram-negative and Gram-positive bacteria. Displays cytotoxic effects on mammalian cell lines (neuronal N2a cells and OLN-93 cells as model systems for nerve cells and glia) acting via disruption of mitochondrial membrane potential, activation of ERK1/2 and induction of HSP32/HO-1 (considered as a sensor of oxidative stress). A broad-spectrum antibiotic agent produced by marine bacteria which does not appear to induce resistance after long-term exposure.
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months

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