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EPZ011989

CAT: 0026-B1221-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B1221-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EPZ011989 is a potent EZH2 inhibitor with Ki values that are less than 3 nM for wild type and Tyr646 mutated EZH2. It displays 15-fold selectivity for EZH2 over EZH1 and is without effect against an array of other lysine methyltransferases. EPZ011989 demonstrates significant tumor growth inhibition in a mouse xenograft model of human B cell lymphoma.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months