EPZ011989

• Target :

  Histone Methyltransferase

• Related Pathways :

  Chromatin/Epigenetic

• Purity :

  0.9981

• Bioactivity :

  EPZ011989 is a effective, specific orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 Y646 and EZH2 wt; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.

• Smiles :

  CCN([C@H]1CC[C@@H](CC1)N(C)CCOC)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C#CCN1CCOCC1

• Molecular Formula :

  C35H51N5O4

• Molecular Weight :

  605.81

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1598383-40-4