EPZ011989

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9981

• Bioactivity:

  EPZ011989 is a effective, specific orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 Y646 and EZH2 wt; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.

• Smiles:

  CCN ([C@H]1CC[C@@H] (CC1) N (C) CCOC) c1cc (cc (C (=O) NCc2c (C) cc (C) [nH]c2=O) c1C) C#CCN1CCOCC1

• Molecular Formula:

  C35H51N5O4

• Molecular Weight:

  605.81

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1598383-40-4