α-Mangostin

• Description :

  α-Mangostin, a naturally occurring xanthone, displays both fast-binding and slow-binding inhibitions to FAS in vitro. It inhibits FAS overall reaction with an IC50 value of 5.54 μM noncompetitively with respect to NADPH, and partially competitively against both substrates acetyl-CoA and malonyl-CoA. Its inhibitory activity is higher than classical FAS inhibitors such as C75, EGCG and curcumin. It induces apoptosis in breast cancer cells by inhibition of FAS.

• Shipping Conditions :

  gel pack

• Storage Conditions :

  -20°C

• Shelf Life :

  36 months