α-Mangostin
CAT:
26-B1059-50
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
α-Mangostin
- Description: α-Mangostin, a naturally occurring xanthone, displays both fast-binding and slow-binding inhibitions to FAS in vitro. It inhibits FAS overall reaction with an IC50 value of 5.54 μM noncompetitively with respect to NADPH, and partially competitively against both substrates acetyl-CoA and malonyl-CoA. Its inhibitory activity is higher than classical FAS inhibitors such as C75, EGCG and curcumin. It induces apoptosis in breast cancer cells by inhibition of FAS.
- Shipping Conditions: gel pack
- Storage Conditions: -20°C
- Shelf Life: 36 months