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Necrosulfonamide

CAT: 0026-9635-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-9635-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Necrosulfonamide is a potent necroptosis inhibitor. It blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Unlike Necrostatin-1 (Cat. No. 1864), NSA does not inhibit the necrosis-induced RIP1 and RIP3 interactions.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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