Products for Research Use Only

HBX-41108

CAT: 0026-9608-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-9608-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HBX-41108 is a potent inhibitor of ubiquitin-specific protease (USP) 7 activity (IC₅₀ = 424 nM). Also inhibits USP7-mediated p53 deubiquitination (IC₅₀ = 0.8 μM). HBX-41108 treatment stabilizes p53, activates the transcription of a p53 target gene without inducing genotoxic stress, and inhibits cancer cell growth. Also induces p53-dependent apoptosis in p53 wild type and isogenic cancer cell lines.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months