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Ezetimibe

CAT: 0026-9468-100Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0026-9468-100Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ezetimibe is a cholesterol transport inhibitor. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. It exhibits IC50 values of 0.0005-0.05 mg/kg in various animal models, selectively blocking cholesterol absorption without inhibiting pancreatic lipolytic enzyme activities in the intestinal lumen, affecting bile acid micelle solubilization of cholesterol, or interfering with the absorption of triglycerides, fatty acids, or bile acids.
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
36 months

Alternative Products

CatalogName
HY-17376-01Ezetimibe

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