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Sildenafil citrate

CAT: 0026-2872-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-2872-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sildenafil citrate is a potent, orally active phosphodiesterase 5 (PDE5) inhibitor (IC₅₀ = 4 nM). Inhibition of PDE5 enhances the relaxation of smooth muscle in a range of vascular tissues by prolonging the nitric oxide/cGMP-mediated activation of cGMP-dependent protein kinase (PKG). Sildenafil also acts as a vasodilator and this property has been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months