Products for Research Use Only

UNC0642

CAT: 0026-2862-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-2862-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UNC0642 is a potent, selective and cell-permeable inhibitor of G9a (EHMT2) and GLP (EHMT1) histone lysine methyltransferases. UNC0642 exhibits an in vitro IC₅₀ <15 nM with selectivity > 100-fold over 13 other HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. In cells, UNC0642 results in a potent reduction of H3K9me2 in MDA MB231 cells with IC₅₀ = 106 nM.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months