YK-4-279

CAT: 0026-2846-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-2846-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YK-4-279 is an Inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. At 10 µM, YK-4-279 blocks RHA binding to ES-FLI1 and induces apoptosis of a panel of Ewing’s sarcoma tumor cell lines with IC₅₀ values ranging from 0.5-2 µM. At 1.5 mg per dose, YK-4-279 reduces the growth of Ewing’s sarcoma orthotopic xenografts in mice after treatment with the inhibitor for two weeks.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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A11612-200YK 4-279 200mg
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