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IWP-3

CAT: 0026-2349-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-2349-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
An inhibitor of Wnt production. Blocks Wnt pathway activity in vitro ( IC₅₀ = 40 nM). IWP-3 inactivates Porcupine (Porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. Through blockade of Wnt signaling, IWP-3 has been used to promote cardiomyocyte generation from human embryonic stem cells (EC₅₀ = 1.2 μM).
Shipping Conditions
gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

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