Products for Research Use Only

LGK974

CAT: 0026-2645-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-2645-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LGK-974 is a potent and specific inhibitor of Porcupine (porcn), a Wnt-specific acyltransferase (IC₅₀ = ~0.4 nM). GK974 potently inhibits Wnt signaling, has strong efficacy in rodent tumor models, and is well-tolerated. In addition, head and neck cancer cell lines with loss-of-function mutations in the Notch signaling pathway have a high response rate to LGK974.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
48 months

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