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LGK974

CAT: 0931-T2618-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T2618-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1243244-14-5
Target
Porcupine
Related Pathways
Stem Cells
Purity
>99.99%
Bioactivity
LGK974 (NVP-LGK974) is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
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Cc1cc(ccn1)-c1ncc(CC(=O)Nc2ccc(cn2)-c2cnccn2)cc1C
Molecular Formula
C23H20N6O
Molecular Weight
396.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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