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CHIR-98014

CAT: 0026-2595-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-2595-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell-permeable. CHIR-98014 is a potent, selective and ATP-competitive inhibitor of GSK3α and GSK3β (IC₅₀ = 0.65 and 0.58 nM, respectively). In addition, CHIR-98014 displays 500 to greater than 1000-fold selectivity towards GSK3 than other protein kinases such as cdc2 and ERK2. CHIR98014 also reduces tau phosphorylation in rat brains and supports Wnt signaling during osteogenesis.
Shipping Conditions
Gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

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