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Bufalin

CAT: 0026-2509-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-2509-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bufalin is cardioactive steroid that exhibits a variety of biological activities, such as cardiotonic, anaesthetic, blood pressure stimulatory, respiratory and antineoplastic effects. Acts as a specific Na⁺/K⁺-ATPase inhibitor. More potent than ouabain. Induces cell differentiation. Induces apoptosis in U937 and HL-60 cells by activation of AP-1 via a MAPK pathway that involves JNK. Regulates Tiam1 gene. Down regulates expression of 14-3-3 protein.
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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