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3-Oxo-bufalin

CAT: 0804-HY-N13080Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N13080Size:1 Each
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Description
3-Oxo-bufalin is an active compound that can be isolated from cultured toad liver tissue. 3-Oxo-bufalin can be produced through a metabolic pathway, and it is a metabolite of Bufalin catalyzed by the stereoselective 3β-dehydrogenase. Bufalin is a Na+/K+-ATPase inhibitor and has anti-tumor activity[1].
CAS Number
4029-65-6
UNSPSC
12352211
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
CANCER
Assay Protocol
https://www.medchemexpress.com/3-oxo-bufalin.html
Smiles
O[C@@]12[C@@]([C@@H](C(C=C3)=COC3=O)CC1)(CC[C@@]4([H])[C@@]2([H])CC[C@@]5([H])[C@@]4(CCC(C5)=O)C)C
Molecular Formula
C24H32O4
Molecular Weight
384.51
References & Citations
[1]Ruan L J, et al. 3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation[J]. Natural Products and Bioprospecting, 2024, 14 (1) : 19.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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