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SGC0946

CAT: 0026-2448-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-2448-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective DOT1L inhibitor (IC₅₀ = 0. 3 nM in a radioactive enzyme assay); >100-fold selective for other histone methyltransferases (HMTs). SGC0946 also potently reduces H3K79 dimethylation with cellular IC₅₀ of 2.6 nM in A431 cells, and 8.8 nM in MCF10A cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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