EPZ-5676

CAT: 0026-2382-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-2382-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective inhibitor of DOT1L methyltransferase (Ki = 80 pM). EPZ-5676 displays 37,000-fold selectivity over all other tested methyltransferases. It inhibits H3K79 methylation and MLL-fusion target gene expression and displays potent cell killing selective for acute leukemia lines bearing MLL translocations.
Shipping Conditions
gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

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