IPA-3

CAT: 0026-2647-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-2647-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IPA-3 is a cell-permeable allosteric inhibitor of PAK1 (tha p21-activated kinase 1) that is non-competitive with respect to ATP binding (IC₅₀ = 2.5 µM). It does not, however, inhibit the activity of PAK1 that has been pre-activated with Cdc42. IPA-3 binds covalently to the PAK1 regulatory domain (apparent Kd = 1.9 uM) and prevents binding to the upstream activator Cdc42. Potential anti-tumor agent.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
48 months

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