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Celastrol

CAT: 0026-1940-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-1940-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell-permeable. An Antioxidant, anti-inflammatory and immunosuppressive agent. Suppresses LPS-induced cytokine release in macrophages and monocytes (IC₅₀ = 40 nM for IL-1β and IL-1α, 80 nM for IL-6, 110 nM for prostaglandin E2 and 210 nM for IL-8 and TNF-α). Suppresses nitric oxide (NO) production (IC₅₀ = 230 nM) and LPS-induced NF-κB activation (IC₅₀ = 270 nM). Inhibits chymotrypsin-like activity of 20S proteasome (IC₅₀ = 2.5 µM) and lipid peroxidation induced by ADP and Fe²⁺ in rat liver mitochondria (IC₅₀ = 7 µM).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

Alternative Products

CatalogName
200694Celastrol

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