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Akt Inhibitor, Isozyme-Selective

CAT: 0026-1708-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-1708-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell-permeable. A potent and selective inhibitor of Akt1/Akt2 activity (IC₅₀ = 58 nM (Akt1), 210 nM (Akt2) and 2.12 µM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50 µM).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months