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Splitomicin

CAT: 0026-1610-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-1610-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Potent inhibitor of yeast NAD⁺-dependent histone deacetylase Sir2p (IC₅₀ = 60 µM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.
Shipping Conditions
RT
Storage Conditions
+4°C
Shelf Life
24months

Alternative Products

CatalogName
A8242-50Splitomicin

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