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HDL Uptake Assay Kit (Fluorometric)

CAT: 0026-K586-100Size: 100 AssaysDry Ice: NoHazardous: No
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CAT#:0026-K586-100Size:100 Assays
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
High-density lipoprotein (HDL) consists of a protein shell, containing apolipoproteins A-I and A-II, and a hydrophobic core consisting of cholesterol and triglycerides surrounded by phospholipids and cholesterol esters. HDL transports cholesterol to the liver or steroidogenic organs such as adrenals, ovary, and testes by both direct and indirect pathways. HDL-Cholesterol is removed by HDL receptors such as scavenger receptor BI (SR-BI), which mediate the selective uptake of cholesterol from HDL. Clinically, high levels of HDL has been associated with cardiovascular health. This is due to the ability of HDL particle to transport cholesterol from lipid-laden macrophages of atherosclerotic arteries to the liver for secretion into the bile by a process called as reverse cholesterol transport. BioVision’s HDL Uptake Assay Kit contains a fluorescently-labeled HDL that can be measured when taken up by cells. Unlabeled-HDL is included in the kit for assay validation.
Applications
• Measure HDL uptake in different cell types • Screen, study or characterize stimulators or inhibitors of HDL uptake
Detection Method
Fluorescence (Ex/Em 540/575 nm)
Features & Benefits
• Only Kit on the market to quantitatively measure HDL uptake. • Includes unlabeled-HDL for assay validation.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
12 months

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