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CHO Host Cell Proteins Elisa kit

CAT: 0026-E4537-100Size: 100 AssaysDry Ice: NoHazardous: No
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CAT#:0026-E4537-100Size:100 Assays
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Description
CHO cell line is widely used in the expression of therapeutic protein , which is a cost effective method for production of commercial quantities of a drug substance. One of the goal in designing a downstream process for biopharmaceutical products is to remove any possible contaminants, including host cell proteins. HCPs can still be present at significant concentrations following several purification steps and can even be co-purified and concentrated with the drug substance itself. HCP in the products will result in adverse toxic or immunological reactions which compromise product safety and quality. This it is desirable to reduce the host cell protein contamination to the lowest level. Therefore, during the development of a downstream process, suitable assays must be available to determine the amount of HCP present.. BioVision’s CHO HCP ELISA kit is a sandwich ELISA assay for the quantitative measurement of CHO HCP in Human serum, plasma and cell culture supernatants. The density of color is proportional to the amount of CHO HCP captured from the samples.
CAS Number
7732-18-5
Reactivity
Universal
Applications
This ELISA kit is used for quantitative measurement of CHO HCP in serum, plasma, tissue homogenates and other biological fluids.
Detection Method
Absorbance (450 nm)
Features & Benefits
Easy, convenient and time-saving method to measure the level of CHO HCP in serum, plasma, tissue homogenates, culture supernatants and other biological fluids. • Detection Range: 0.1 - 100 ng/ml • Sensitivity: < 0.31 ng/ml • Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10% • This assay has high sensitivity and excellent specificity for detection of CHO HCP. No significant cross-reactivity or interference between CHO HCP and analogues was observed.
Shipping Conditions
gel pack
Storage Conditions
4°C
Shelf Life
12 months

Chemical Information

Water

Water is an oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms. It has a role as an amphiprotic solvent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, a member of greenhouse gas, an Escherichia coli metabolite and a human metabolite. It is an oxygen hydride, a mononuclear parent hydride and an inorganic hydroxy compound. It is a conjugate base of an oxonium. It is a conjugate acid of a hydroxide.

CAS Number7732-18-5
PubChem CID962
IUPAC Nameoxidane
Molecular FormulaH2O
Molecular Weight18.015
XLogP-0.5
Topological Polar Surface Area1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Heavy Atom Count1
Formal Charge0
Complexity0
SMILES
O
InChI
InChI=1S/H2O/h1H2
InChIKey
XLYOFNOQVPJJNP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Water
CAS: 7732-18-5
CID: 962
Formula: H2O
MW: 18.015
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight18.015
XLogP3-0.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass18.010564683
Monoisotopic Mass18.010564683
Topological Polar Surface Area1 Ų
Heavy Atom Count1
Formal Charge0
Complexity0
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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