QuickDetect™ GDNF (Human) ELISA Kit

QuickDetect™ GDNF (Human) ELISA Kit

• Description: Glial cell line-derived neurotrophic factor (GDNF) was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung's disease. BioVision’s GDNF ELISA kit is a sandwich ELISA assay for the quantitative measurement of Human GDNF in serum, plasma and cell culture supernatants in 90 minutes. The density of color is proportional to the amount of Human GDNF captured from the samples.
• CAS Number: 7732-18-5
• Reactivity: Human
• Applications: This ELISA kit is used for quantitative measurement of total GDNF in human serum, plasma, urine, cell culture samples, biological fluid.
• Detection Method: Absorbance (450 nm)
• Features & Benefits: Recovery rate: < 100 ± 30% with normal human serum samples with known concentrations
• Shipping Conditions: gel pack
• Storage Conditions: 4°C
• Shelf Life: 6 months