BCN-SS-NHS

• UNSPSC Description:

  BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bcn-ss-nhs.html

• Smiles:

  O=C(NCCSSCCC(ON1C(CCC1=O)=O)=O)OC[C@H]2[C@@]3([H])CCC#CCC[C@@]23[H]

• Molecular Weight:

  454.56

• References & Citations:

  [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

• Shipping Conditions:

  Blue Ice