BCN-PEG4-NHS ester

• UNSPSC Description:

  BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bcn-peg4-nhs-ester.html

• Smiles:

  [H][C@@]12[C@@](CCC#CCC2)([H])[C@@H]1COC(NCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O)=O

• Molecular Weight:

  538.59

• References & Citations:

  [1]"An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. "

• Shipping Conditions:

  Blue Ice