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BAP1-IN-1

CAT: 0804-HY-W327122-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W327122-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAP1-IN-1 (Compound 8) is a BRCA1 associated protein 1 (BAP1) catalytic activity inhibitor with an IC50 of 0.1-1 μM[1].
CAS Number
353495-21-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bap1-in-1.html
Purity
99.86
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=[N+](C1=CC2=C(NC(C3=CC=CC=C3)C4C2C=CC4)C=C1)[O-]
Molecular Formula
C18H16N2O2
Molecular Weight
292.33
Precautions
H302, H315, H319
References & Citations
[1]Wang L, et al. Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia. Nat Cancer. 2021 May;2 (5) :515-526.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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