D-Pinitol

• Description:

  D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system[1][2]. D-pinitol has antiviral and larvicidal activities[3].

• Product Name Alternative:

  3-O-Methyl-D-chiro-inositol

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H332, H335

• Target:

  Influenza Virus

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Infection; Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/d-pinitol.html

• Concentration:

  10mM

• Purity:

  99.79

• Solubility:

  DMSO : 116.67 mg/mL (ultrasonic)

• Smiles:

  O[C@@H]1[C@@H]([C@H]([C@@H]([C@H]([C@H]1O)O)O)OC)O

• Molecular Formula:

  C7H14O6

• Molecular Weight:

  194.18

• Precautions:

  H302, H315, H319, H332, H335

• References & Citations:

  [1]Gao Y, et al. Effects of D-Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2Diabetes Mellitus Rats. J Agric Food Chem. 2015 Jul 8;63 (26) :6019-26.|[2]Moreira LN, et al. Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in MouseMesenteric Artery. Front Pharmacol. 2018 May 22;9:528.|[3]Rengarajan T, et al. D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB. Asian Pac J Cancer Prev. 2014;15 (4) :1757-62.|[4]Sethi G, et al. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis. Mol Cancer Ther. 2008 Jun;7 (6) :1604-14.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 2

• CAS Number:

  10284-63-6