REDV

CAT: 0804-HY-P3522-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P3522-01Size:5 mg
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Description
REDV is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. REDV can mediate adhesion to the IIICS region of plasma fibronectin by binding the integrin alpha 4 beta 1 (α4β1) . REDV can be used for the research of cell adhesion. REDV is used to study the effects of gene vectors containing REDV on cells[1][2].
CAS Number
[107978-83-6]
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/redv.html
Purity
99.33
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C20H35N7O9
Molecular Weight
517.53
References & Citations
[1]S P Massia, et al. Vascular endothelial cell adhesion and spreading promoted by the peptide REDV of the IIICS region of plasma fibronectin is mediated by integrin alpha 4 beta 1. J Biol Chem. 1992 Jul 15;267 (20) :14019-26.|[2]Lv J, et al. Star-shaped copolymer grafted PEI and REDV as a gene carrier to improve migration of endothelial cells. Biomater Sci. 2017 Feb 28;5 (3) :511-522.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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