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Ruthenium red

CAT: 0804-HY-103311-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103311-01Size:100 mg
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Description
Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker[1][2].
CAS Number
11103-72-3
Product Name Alternative
Ammoniated ruthenium oxychloride
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel
Type
Dye Reagents
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ruthenium-red.html
Purity
99.95
Solubility
H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[NH3][Ru](O[Ru]([NH3])([NH3])([NH3])([NH3])O[Ru]([NH3])([NH3])([NH3])([NH3])[NH3])([NH3])([NH3])([NH3])[NH3].[6+].[Cl-].[6]
Molecular Formula
[ (NH3) 5RuORu (NH3) 4ORu (NH3) 5]Cl6
Molecular Weight
786.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Lashanda N Waller, et al. Ruthenium red staining for ultrastructural visualization of a glycoprotein layer surrounding the spore of Bacillus anthracis and Bacillus subtilis. J Microbiol Methods. 2004 Jul;58 (1) :23-30.|[2]Claire O Malécot, et al. Ruthenium red as an effective blocker of calcium and sodium currents in guinea-pig isolated ventricular heart cells. Br J Pharmacol. 1998 Jun; 124 (3) : 465-472.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
L-type calcium channel

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