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Neostenine

CAT: 0804-HY-N3197Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N3197Size:1 Each
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Description
Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application[1][2].
CAS Number
477953-07-4
Product Name Alternative
(+) -Neostenine
UNSPSC
12352005
Target
P-glycoprotein
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/neostenine.html
Solubility
10 mM in DMSO
Smiles
CC[C@@H]1[C@]2([H])[C@]3([H])[C@](CCN3CCCC2)([H])[C@@]4([H])[C@]1([H])OC([C@H]4C)=O
Molecular Formula
C17H27NO2
Molecular Weight
277.40
References & Citations
[1]Chung HS, et al. Antitussive activity of Stemona alkaloids from Stemona tuberosa. Planta Med. 2003 Oct;69 (10) :914-20.|[2]Leung PH, et al. Intestinal absorption of Stemona alkaloids in a Caco-2 cell model. Planta Med. 2006 Feb;72 (3) :211-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19180948Neostenine

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