DSPE-PEG-DBCO, MW 2000

• UNSPSC Description:

  DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery[1]. DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• Target Antigen:

  Liposome

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dspe-peg-dbco-mw-2000.html

• Purity:

  99.08

• Solubility:

  DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  CCCCCCCCCCCCCCCCCC(OC[C@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COP(O)(OCCNC(OCCNC(CCCCC(N1C(C=CC=C2)=C2C#CC(C=CC=C3)=C3C1)=O)=O)=O)=O)=O.[n]

• Molecular Weight:

  2000(Average)

• References & Citations:

  [1]Oude Blenke E, et al. Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger. Bioconjug Chem. 2017 Feb 15;28(2):574-582.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported