Products for Research Use Only
RegisterLogin

Ipratropium (bromide)

CAT: 0804-HY-B0241-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0241-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ipratropium bromide (Sch 1000) is a muscarinic receptor antagonist, with IC50s of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide relaxes smooth muscle, can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma[1][2][3][4][5].
CAS Number
22254-24-6
Product Name Alternative
Sch 1000
UNSPSC
12352005
Hazard Statement
H302, H319, H332
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Ipratropium-bromide.html
Purity
99.92
Solubility
DMSO : ≥ 35 mg/mL|H2O : 100 mg/mL (ultrasonic)
Smiles
C[N+]1([C@H]2CC[C@H]1CC(OC(C(CO)C3=CC=CC=C3)=O)C2)C(C)C.[Br-]
Molecular Formula
C20H30BrNO3
Molecular Weight
412.36
Precautions
H302, H319, H332
References & Citations
[1]Fryer AD, et al. Maclagan, Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig. Eur J Pharmacol, 1987. 139 (2) : p. 187-91.|[2]Harvey, et al. Maddock, Ipratropium Bromide-Mediated Myocardial Injury in In Vitro Models of Myocardial Ischaemia/Reperfusion. Toxicol Sci, 2014.|[3]Maria Prat, et al. Discovery of novel quaternary ammonium derivatives of (3R) -quinuclidinyl amides as potent and long acting muscarinic antagonists. Bioorg Med Chem Lett. 2015 Apr 15;25 (8) :1736-1741.|[4]Wenhui Zhang, et al. Anti-inflammatory effects of formoterol and ipratropium bromide against acute cadmium-induced pulmonary inflammation in rats. Eur J Pharmacol. 2010 Feb 25;628 (1-3) :171-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MAChR1; mAChR2; mAChR3

Related Products

CatalogName
HY-B0241S1Ipratropium-d7 (bromide)
HY-B0241S-01Ipratropium-d3 (bromide)
HY-W758392(±) -Ipratropium-d3 Bromide (N-methyl-d3)
HY-129948S-01Ipratropium-d3 (iodide)
HY-W740050Ipratropium-d3 Iodide
HY-172342MitoA (bromide)
HY-Y1100-01Cyclopropylmethyl bromide
HY-106024AAlagebrium (bromide)
HY-131119-01Dimethyldioctadecylammonium (bromide)
HY-164183Trimethaphan (bromide)

Alternative Products

CatalogName
FI44992-01Ipratropium bromide
CS-T-93876Ipratropium-d7 Bromide
RM-I091618-01Ipratropium-D3 Bromide
GL5159-250mgIpratropium bromide monohydrate

Popular Products