Products for Research Use Only
RegisterLogin

Neorauflavane

CAT: 0804-HY-N3200Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N3200Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Neorauflavane is a potent tyrosinase inhibitor derived from Campylotropis hirtella, with an IC50 value of 30 nM for tyrosinase monophenolase activity and an IC50 value of 500 nM for diphenolase activity. Neorauflavane can effectively reduce the melanin content of B16 melanoma cells[1].
CAS Number
53734-74-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/neorauflavane.html
Purity
96.0
Solubility
10 mM in DMSO
Smiles
COC1=C2C(OC[C@@H](C3=C(C=C(O)C=C3)O)C2)=CC4=C1C=CC(C)(C)O4
Molecular Formula
C21H22O5
Molecular Weight
354.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Xuefei Tan, et al. Highly potent tyrosinase inhibitor, neorauflavane from Campylotropis hirtella and inhibitory mechanism with molecular docking. Bioorg Med Chem. 2016 Jan 15;24 (2) :153-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N3199-01Neorauflavene

Alternative Products

CatalogName
380930Neorauflavane

Popular Products