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PAX6 Antibody

CAT: 0013-GTR18574009Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18574009Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAX6 is a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [RefSeq]
Reactivity
Human
Immunogen
A partial human PAX6 protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Clone
PBPX6
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein G purified antibody
Dilution
Western blot: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
Tested Applications
WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

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