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BOB1 Antibody

CAT: 0013-GTR18573797Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18573797Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. [UniProt]
UniProt
Q16633
Reactivity
Human
Immunogen
A portion of amino acids 148-255 from the human protein was used as the immunogen for the BOB1 antibody.
Clonality
Monoclonal
Clone
PD2AF1-1
Conjugation
Unconjugated
Field of Research
Cancer Biology
Purification
Protein G affinity
Dilution
Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The stated application concentrations are suggested starting points. Titration of the BOB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2b, kappa

UniProtKB · Q16633

POU domain class 2-associating factor 1

OBF1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16633
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POU2AF1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R8Z9, Q14983
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Activator

Coding sequence diversity

Chromosomal rearrangement

Cellular component

Nucleus

Disease

Proto-oncogene

Biological process

TranscriptionTranscription regulation

PTM

Ubl conjugation

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