Products for Research Use Only
RegisterLogin

CDC2 Antibody / CDK1

CAT: 0013-GTR18573677Size: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18573677Size:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recognizes a 34kDa protein (cdk1), identified as Cdk1/Cdc2/p34cdc2 (a catalytic subunit of Maturation Promoting Factor) . Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2) . It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This mAb reportedly inhibits the activation of p34cdc2 kinase by cyclins.
UniProt
P06493
Reactivity
Human, Mouse, Rat
Immunogen
A partial protein (the C-terminal two-thirds of Xenopus CDC2) was used as the immunogen for this CDC2 antibody.
Clonality
Monoclonal
Clone
A17.1.1
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein G purified antibody
Dilution
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CDC2 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Isotype
Mouse IgG2a, kappa

Related Products

CatalogName
GTR18225318CDK1/CDC2 Antibody
GTR18571883CDK1 Antibody / CDC2
GTR18574167CDK1 Antibody / CDC2
GTR18082366-01CDK1 Antibody / CDC2
GTR18080932-01CDK1 Antibody / CDC2
GTR18198763Cdk1/Cdc2 Polyclonal Antibody
GTR18064892-01Cdk1/Cdc2 Polyclonal Antibody
GTR18047600-01Cdk1/Cdc2 monoclonal antibody
GTR17691653CDK1/Cdc2 Rabbit Monoclonal Antibody
GTR18277858Cdk1/Cdc2 Polyclonal Conjugated Antibody

Alternative Products

CatalogName
AF7774-01CDK1/CDC2 Antibody
RQ5151CDC2 Antibody / CDK1
RQ5143CDK1 Antibody / CDC2
N0857-01CDC2/CDK1 Antibody
521326-01CDK1/CDC2

Popular Products