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Recombinant Human IgG Antibody

CAT: 0013-GTR18573504Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18573504Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
UniProt
P01857
Reactivity
Human
Immunogen
Human Ig Gamma Chain was used as the immunogen for this recombinant human IgG antibody.
Clonality
Recombinant
Clone
RIG266
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The optimal dilution of the recombinant human IgG antibody for each application should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · P01857

Immunoglobulin heavy constant gamma 1

IGHG1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01857
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IGHG1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A0A0MS08
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Cellular component

Cell membraneImmunoglobulinMembraneSecreted

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainTransmembraneTransmembrane helix

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