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Lithospermic acid (Standard)

CAT: 0804-HY-N0823R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0823R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lithospermic acid (Standard) is the analytical standard of Lithospermic acid. This product is intended for research and analytical applications. Lithospermic acid ((+) -Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4) -induced acute liver damage in vitro and in vivo[1].
CAS Number
28831-65-4
Product Name Alternative
(+) -Lithospermic acid (Standard)
UNSPSC
12352005
Target
AMPK; Apoptosis; Keap1-Nrf2; NO Synthase; Reference Standards; Xanthine Oxidase
Type
Reference Standards
Related Pathways
Apoptosis; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; PI3K/Akt/mTOR
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lithospermic-acid-standard.html
Smiles
O=C([C@@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=C(O)C=CC(/C=C/C(O[C@@H](C(O)=O)CC4=CC=C(O)C(O)=C4)=O)=C13)O
Molecular Formula
C27H22O12
Molecular Weight
538.46
References & Citations
[1]Chan KW, et al. Anti-oxidative and hepatoprotective effects of lithospermic acid against carbon tetrachloride-induced liver oxidative damage in vitro and in vivo. Oncol Rep. 2015 Aug;34 (2) :673-80.|[2]Zhang M, et al., Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα) . Front Pharmacol. 2021 Nov 26;12:794982.|[3]Liu X, et al., Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats. Chem Biol Interact. 2008 Nov 25;176 (2-3) :137-42.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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