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AZD3988

CAT: 0804-HY-50861-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-50861-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD3988 is an orally active diacylglycerol acyl transferase-1 (DGAT-1) inhibitor. AZD3988 has excellent DGAT-1 (human) potency with an IC50 value of 0. 6 nM. AZD3988 can be used for the research of metabolic diseases such as diabetes, obesity[1].
CAS Number
[892489-52-0]
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/azd3988.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C=C1)[C@H](CC2)CC[C@@H]2CC(O)=O)C3=NN=C(NC4=CC=C(C(F)=C4)F)O3
Molecular Formula
C23H22F2N4O4
Molecular Weight
456.44
References & Citations
[1]McCoull W, et al. Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes. Bioorg Med Chem Lett. 2012 Jun 15;22 (12) :3873-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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