Products for Research Use Only
RegisterLogin

CD105 Antibody / Endoglin

CAT: 0013-GTR18573236Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18573236Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. CD105 has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. It is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.
UniProt
P17813
Reactivity
Human
Immunogen
A partial recombinant protein corresponding to amino acids 74-251 of human CD105/Endoglin was used as the immunogen for the CD105 antibody.
Clonality
Monoclonal
Clone
ENG/1326
Conjugation
Unconjugated
Field of Research
Cardiovascular Research; Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
Western blot: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Titering of the CD105 antibody may be required for optimal performance.
Tested Applications
WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · P17813

Endoglin

EGLN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17813
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ENG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q14248, Q14926, Q5T9C0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisCell adhesion

Cellular component

Cell membraneMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

Related Products

CatalogName
GTR18573237Endoglin Antibody / CD105
GTR18083096-01Endoglin Antibody / CD105
GTR18205256-01Endoglin / CD105 Antibody
GTR18205255-01Endoglin / CD105 Antibody
GTR18081744-01Endoglin Antibody / CD105
GTR18312213-01Endoglin/CD105 Antibody
GTR18575251Endoglin Antibody / CD105
GTR18317390Endoglin Antibody / ENG / CD105
GTR18311056-01Endoglin/CD105 Antibody (MMAE)
GTR18317379-01ENG Antibody / Endoglin / CD105

Alternative Products

CatalogName
V8568-20UGEndoglin Antibody / CD105
V5311-100UGCD105 Antibody / Endoglin
E80902-1CD105 (Endoglin) Antibody
GWB-846D80CD105. ENDOGLIN, Antibody
CAF50467Endoglin/CD105 antibody
CST 3290SCD105/Endoglin Antibody
OASL01114-50ULCD105, Endoglin Antibody
MBS9510620-01Anti-CD105 (Endoglin) Antibody [ABT-CD105]
MBS2575351-01CD105/Endoglin Polyclonal Antibody
V5310-20UGENG Antibody / Endoglin / CD105

Popular Products