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Galectin 1 Antibody

CAT: 0013-GTR18573161Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18573161Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
UniProt
P09382
Reactivity
Human
Immunogen
A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.
Clonality
Monoclonal
Clone
GAL1/1831
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
ELISA: 2-4ug/ml (order BSA/azide-free format), Immunofluorescence: 1-2ug/ml, Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 0.5-1ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Titering of the Galectin 1 antibody may be required for optimal performance.
Tested Applications
ELISA, IF, IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, lambda

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