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CD70 Antibody

CAT: 0013-GTR18572942Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18572942Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
UniProt
P32970
Reactivity
Human
Immunogen
The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.
Clonality
Monoclonal
Clone
BU69
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-3ug/ml, Immunohistochemistry: 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CD70 antibody should be determined by the researcher.1. This mAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Tested Applications
FACS, IF, IHC
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

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