Products for Research Use Only

CD47 Antibody Cocktail

CAT: 0013-GTR18572922Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18572922Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
UniProt
Q08722
Reactivity
Human
Immunogen
Recombinant human protein (IAP/964) and intact CD47 purified from placenta (B6H12.2) were used as the immunogen for the CD47 antibody cocktail.
Clonality
Monoclonal
Clone
IAP/964 + B6H12.2
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation; Cell Biology
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CD47 antibody cocktail should be determined by the researcher.
Tested Applications
FACS, IF
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · Q08722

Leukocyte surface antigen CD47

CD47_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q08722
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD47
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K198, D3DN59, Q53Y71, Q96A60
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisApoptosisCell adhesionInflammatory response

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoproteinPyrrolidone carboxylic acid

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix