Products for Research Use Only
RegisterLogin

NCAM Antibody

CAT: 0013-GTR18572606Size: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18572606Size:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This mAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas) . It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma) . Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
UniProt
P13591
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the NCAM antibody.
Clonality
Monoclonal
Clone
NCAM1/784
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the NCAM antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Isotype
Mouse IgG1, kappa

Related Products

CatalogName
GTR17692600NCAM NCAM1 Rabbit Monoclonal Antibody
GTR18273979NCAM Conjugated Antibody
GTR18318324CD56 Antibody / NCAM
GTR18224955NCAM/CD56 Antibody
GTR18224189NCAM/CD56 Antibody
GTR18074374-01NCAM-L1 Antibody
GTR18224954NCAM/CD56 Antibody
GTR18224732NCAM/CD56 Antibody
GTR18222056NCAM/CD56 Antibody
GTR18288409NCAM Conjugated Antibody

Alternative Products

CatalogName
GWB-C7A40CNCAM Antibody
GWB-C0A0F4NCAM, Antibody
MA1068Anti-NCAM Antibody (monoclonal, NCAM-0B11)
abx216508-01NCAM-L1/L1CAM (NCAM-L1) Antibody
GWB-A54980NCAM Antibody (PE)
MBS8534351-01NCAM

Popular Products