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Recombinant SDHB Antibody

CAT: 0013-GTR18571763Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18571763Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a key component of the citric acid cycle and the electron transport chain, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas and gastrointestinal stromal tumors. A subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.
UniProt
P21912
Reactivity
Human
Immunogen
A synthetic peptide specific to human SDHB was used as the immunogen for the recombinant SDHB antibody.
Clonality
Recombinant
Clone
SDHB/6697R
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant SDHB antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG

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