Products for Research Use Only
RegisterLogin

Basic Cytokeratin Antibody

CAT: 0013-GTR18574495Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18574495Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1) ; 64kDa (CK3) ; 59kDa (CK4) ; 58kDa (CK5) ; 56kDa (CK6) ; 52kDa (CK8) . Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
UniProt
Q01546
Reactivity
Human
Immunogen
Solubilized cytokeratin extract from human stratum corneum was used as the immunogen.
Clonality
Monoclonal
Clone
SPM116
Conjugation
Unconjugated
Field of Research
Neuroscience
Purification
Protein G purified
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Differences in protocols and secondaries may cause the Basic Cytokeratin antibody to need titering for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1

Related Products

CatalogName
GTR18576943CYTOKERATIN AE3 BASIC Antibody
GTR18293194Cytokeratin, Multi (Basic) Antibody
GTR18292879Cytokeratin, Multi (Basic) Antibody
GTR18292768Cytokeratin, Multi (Basic) Antibody
GTR18292023Cytokeratin, Multi (Basic) Antibody
GTR18293193Cytokeratin, Multi (Basic) Antibody
GTR18128821Pan Cytokeratin (Acidic and Basic) Antibody
GTR18317304Pan Cytokeratin Antibody Cocktail (Acidic + Basic)
GTR18575120Pan Cytokeratin Antibody Cocktail (Acidic + Basic)
GTR18572266HMW Cytokeratin Antibody / Basic / Type II

Alternative Products

CatalogName
V3106-100UGBasic Cytokeratin Antibody
V4282-20UGRecombinant Basic Cytokeratin Antibody
33-544Basic Cytokeratin Antibody [SPM591]
33-940Basic Cytokeratin Antibody [BCCK1-1]
33-549Basic Cytokeratin Antibody [KRTH/1076]
GWB-B90349basic Cytokeratin Antibody (ready-to-use)
589966Cytokeratin, Basic
sc-70402Basic Cytokeratin (3G129)
sc-57004Basic Cytokeratin (AE3)

Popular Products